Herman's Head was a Fox series. The premise was that there was a guy whose thoughts would be shown intermittently throughout the show (its a hard premise to explain). Molly played the angelic or good part of Herman's brain, while 3 other characters played the other parts. As happens with some of these "high premise" shows, the show got really funny, due mainly to good writing and fine acting by a good cast. This humour then sort of outweighed the original premise, which was kind of stupid. Therefore, they stopped highlighting the premise as much as the show went on.

Looking pouty. Source: Contribution.

With the rest of the "head". Source: Contribution.